It’s time

Multiple hypotheses suggest
mechanisms of disease
may be behind

Actor portrayal.

Depression is one of the leading causes of disability worldwide.4 Many patients may fail to achieve optimal clinical outcomes despite ongoing management.5 Evidence suggests that early response matters.6,7

Scientific discoveries regarding the role of certain pathways, including inhibitory and excitatory signaling in the brain, may give us a different perspective on depression and its treatment.8

Early response
may determine
long-term success

Learn about the important link between earlier response to antidepressants and improved patient outcomes.

Review the data
The real-world
effects of

See how the challenges of depression management can negatively impact patient outcomes.

Learn about their reality
See the latest

Re-examine depression. Follow us on the journey forward. Stay up-to-date with scientific advances.

Sign up

Looking beyond monoamines

Learn about the neurochemical systems, including excitatory and inhibitory signaling, that may play a role in depression.

Stay up-to-date

Follow the science of depression.

(All fields with an * are required)

Thank you for signing up!

We'll keep you informed as we move forward with the science of depression.

Read about the reality of depression